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Inhibition of PDE4 protects neurons against oxygen-glucose  deprivation-induced endoplasmic reticulum stress through activation of the  Nrf-2/HO-1 pathway - ScienceDirect
Inhibition of PDE4 protects neurons against oxygen-glucose deprivation-induced endoplasmic reticulum stress through activation of the Nrf-2/HO-1 pathway - ScienceDirect

RCSB PDB - 5K1I: PDE4 crystal structure in complex with small molecule  inhibitor
RCSB PDB - 5K1I: PDE4 crystal structure in complex with small molecule inhibitor

PDE4 inhibition: a novel approach for the treatment of inflammatory bowel  disease: Trends in Pharmacological Sciences
PDE4 inhibition: a novel approach for the treatment of inflammatory bowel disease: Trends in Pharmacological Sciences

PDE4 inhibitors in COPD—a more selective approach to treatment -  Respiratory Medicine
PDE4 inhibitors in COPD—a more selective approach to treatment - Respiratory Medicine

Frontiers | Phosphodiesterase-4 Inhibitors for the Treatment of  Inflammatory Diseases | Pharmacology
Frontiers | Phosphodiesterase-4 Inhibitors for the Treatment of Inflammatory Diseases | Pharmacology

Phosphodiesterase Inhibitors: What Are They, How Do They Work, What Are  They Used For, and More | Osmosis
Phosphodiesterase Inhibitors: What Are They, How Do They Work, What Are They Used For, and More | Osmosis

Phosphodiesterase 4 inhibitors - Journal of the American Academy of  Dermatology
Phosphodiesterase 4 inhibitors - Journal of the American Academy of Dermatology

Phosphodiesterase-4 enzyme as a therapeutic target in neurological  disorders - ScienceDirect
Phosphodiesterase-4 enzyme as a therapeutic target in neurological disorders - ScienceDirect

Combined-inhibition-of-phosphodiesterase-PDE3-and-PDE4-inhibitors-has-additive-and  – Dr. Mahler
Combined-inhibition-of-phosphodiesterase-PDE3-and-PDE4-inhibitors-has-additive-and – Dr. Mahler

GSK356278 is a Selective and Orally Bioavailable PDE4 Inhibitor - Immune  System Research
GSK356278 is a Selective and Orally Bioavailable PDE4 Inhibitor - Immune System Research

Design, synthesis, and biological evaluation of novel catecholopyrimidine  based PDE4 inhibitor for the treatment of atopic dermatitis - ScienceDirect
Design, synthesis, and biological evaluation of novel catecholopyrimidine based PDE4 inhibitor for the treatment of atopic dermatitis - ScienceDirect

PDE4 Inhibitors, Boehringer Ingelheim Pharmaceuticals | New Drug Approvals
PDE4 Inhibitors, Boehringer Ingelheim Pharmaceuticals | New Drug Approvals

Phosphodiesterase inhibitors - Knowledge @ AMBOSS
Phosphodiesterase inhibitors - Knowledge @ AMBOSS

Targeted Delivery of an Anti-inflammatory PDE4 Inhibitor to Immune Cells  via an Antibody–drug Conjugate: Molecular Therapy
Targeted Delivery of an Anti-inflammatory PDE4 Inhibitor to Immune Cells via an Antibody–drug Conjugate: Molecular Therapy

PLOS ONE: Potent PDE4 inhibitor activates AMPK and Sirt1 to induce  mitochondrial biogenesis
PLOS ONE: Potent PDE4 inhibitor activates AMPK and Sirt1 to induce mitochondrial biogenesis

Phosphodiesterase-4 inhibitor - Wikipedia
Phosphodiesterase-4 inhibitor - Wikipedia

R)-(-)-Rolipram, Selective PDE4 inhibitor (CAS 85416-75-7) (ab120031) |  Abcam
R)-(-)-Rolipram, Selective PDE4 inhibitor (CAS 85416-75-7) (ab120031) | Abcam

The PDE4 inhibitor CHF6001 modulates pro-inflammatory cytokines, chemokines  and Th1- and Th17-polarizing cytokines in human dendritic cells -  ScienceDirect
The PDE4 inhibitor CHF6001 modulates pro-inflammatory cytokines, chemokines and Th1- and Th17-polarizing cytokines in human dendritic cells - ScienceDirect

Frontiers | Phosphodiesterase-4 Inhibitors for the Treatment of  Inflammatory Diseases | Pharmacology
Frontiers | Phosphodiesterase-4 Inhibitors for the Treatment of Inflammatory Diseases | Pharmacology

The effect and associated mechanism of action of phosphodiesterase 4 (PDE4)  inhibitor on CD4+ lymphocyte proliferation - Kim - 2021 - Clinical and  Experimental Pharmacology and Physiology - Wiley Online Library
The effect and associated mechanism of action of phosphodiesterase 4 (PDE4) inhibitor on CD4+ lymphocyte proliferation - Kim - 2021 - Clinical and Experimental Pharmacology and Physiology - Wiley Online Library

Rolipram is a Selective Phosphodiesterases PDE4 Inhibitor - Immune System  Research
Rolipram is a Selective Phosphodiesterases PDE4 Inhibitor - Immune System Research

The role of phosphodiesterase 4 in the pathophysiology of atopic dermatitis  and the perspective for its inhibition - Guttman‐Yassky - 2019 -  Experimental Dermatology - Wiley Online Library
The role of phosphodiesterase 4 in the pathophysiology of atopic dermatitis and the perspective for its inhibition - Guttman‐Yassky - 2019 - Experimental Dermatology - Wiley Online Library

PDE4 subtypes in cancer | Oncogene
PDE4 subtypes in cancer | Oncogene

Frontiers | Tanimilast, A Novel Inhaled Pde4 Inhibitor for the Treatment of  Asthma and Chronic Obstructive Pulmonary Disease | Pharmacology
Frontiers | Tanimilast, A Novel Inhaled Pde4 Inhibitor for the Treatment of Asthma and Chronic Obstructive Pulmonary Disease | Pharmacology

Apremilast: a novel PDE4 inhibitor in the treatment of autoimmune and  inflammatory diseases | Semantic Scholar
Apremilast: a novel PDE4 inhibitor in the treatment of autoimmune and inflammatory diseases | Semantic Scholar

PDE4 inhibition reduces the release of a variety of pro-inflammatory... |  Download Scientific Diagram
PDE4 inhibition reduces the release of a variety of pro-inflammatory... | Download Scientific Diagram